Computational study to discover potent phytochemical inhibitors against drug target, squalene synthase from Leishmania donovani

Aims: The parasite, Leishmania donovani is responsible for lethal visceral leishmaniasis (VL) in humans. There is a need to investigate novel medicines as antileishmanial drugs, as medication currently introduced for leishmaniasis may cause resistance, serious side-effects, chemical instability and...

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Bibliographic Details
Main Authors: Padmika Madushanka Wadanambi, Uthpali Mannapperuma
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021012810