The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas

The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas

<p>Abstract</p> <p>Background</p> <p>The PI3K/Akt pathway is involved in cellular survival pathways by inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative prognostic value has been proven in many types of cancer. In soft tissue sar...

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Bibliographic Details
Main Authors: Valkov Andrej, Kilvaer Thomas K, Sorbye Sveinung W, Donnem Tom, Smeland Eivind, Bremnes Roy M, Busund Lill-Tove
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Translational Medicine
Subjects:
soft tissue sarcomas
Akt isoforms
PI3K
PTEN
ER
PgR
disease-specific survival
Online Access:http://www.translational-medicine.com/content/9/1/200

Internet

http://www.translational-medicine.com/content/9/1/200

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