Comparing Targeted vs. Untargeted MS<sup>2</sup> Data-Dependent Acquisition for Peak Annotation in LC–MS Metabolomics

Comparing Targeted vs. Untargeted MS<sup>2</sup> Data-Dependent Acquisition for Peak Annotation in LC–MS Metabolomics

One of the most widely used strategies for metabolite annotation in untargeted LCMS is based on the analysis of MS<sup>n</sup> spectra acquired using data-dependent acquisition (DDA), where precursor ions are sequentially selected from MS scans based on user-selected criteria. However, t...

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Bibliographic Details
Main Authors: Isabel Ten-Doménech, Teresa Martínez-Sena, Marta Moreno-Torres, Juan Daniel Sanjuan-Herráez, José V. Castell, Anna Parra-Llorca, Máximo Vento, Guillermo Quintás, Julia Kuligowski
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Metabolites
Subjects:
liquid chromatography–mass spectrometry
peak annotation
data dependent acquisition
human milk
Online Access:https://www.mdpi.com/2218-1989/10/4/126

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https://www.mdpi.com/2218-1989/10/4/126

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