Renal Phosphate Handling: Independent Effects of Circulating FGF23, PTH, and Calcium

ABSTRACT Excess fibroblast growth factor 23 (FGF23), excess PTH, and an increase in extracellular calcium cause hypophosphatemia by lowering the maximum renal phosphate reabsorption threshold (TmP/GFR). We recently reported two cases of X‐linked hypophosphatemia (XLH) with severe tertiary hyperparat...

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Bibliographic Details
Main Authors: Malachi J McKenna, Rachel K Crowley, Patrick J Twomey, Mark T Kilbane
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:JBMR Plus
Subjects:
Online Access:https://doi.org/10.1002/jbm4.10437