Hydro-alcoholic extract of Matricaria recutita exhibited dual anti-spasmodic effect via modulation of Ca2+ channels, NO and PKA2-kinase pathway in rabbit jejunum

Objective: Several studies have shown the antispasmodic activity of Matricariarecutita without detailing the underlying mechanism(s). The present study was designed to determine whether the antispasmodic mechanisms of M. recutita extract mediated via histaminergic/cholinergic receptors, Ca2+channels...

Full description

Bibliographic Details
Main Authors: Hamidreza yazdi, Akhtar Seifi, Shima Changizi, Vahid Khori, Fatemeh Hossini, Ali Davarian, Yahya Jand, Ayesheh Enayati, Masumeh Mazandarani, Fateme Nanvabashi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-06-01
Series:Avicenna Journal of Phytomedicine
Subjects:
Online Access:http://ajp.mums.ac.ir/article_8607_530b34da8485e1a892c902902e7ebdba.pdf