Paracrine Fibroblast Growth Factor Initiates Oncogenic Synergy with Epithelial FGFR/Src Transformation in Prostate Tumor Progression

Cross talk of stromal-epithelial cells plays an essential role in both normal development and tumor initiation and progression. Fibroblast growth factor (FGF)-FGF receptor (FGFR)-Src kinase axis is one of the major signal transduction pathways to mediate this cross talk. Numerous genomic studies hav...

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Bibliographic Details
Main Authors: Qianjin Li, Lishann Ingram, Sungjin Kim, Zanna Beharry, Jonathan A. Cooper, Houjian Cai
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558617305055