Significance of Phosphorylated Epidermal Growth Factor Receptor and Its Signal Transducers in Human Soft Tissue Sarcoma

Significance of Phosphorylated Epidermal Growth Factor Receptor and Its Signal Transducers in Human Soft Tissue Sarcoma

Previous studies have shown that total epidermal growth factor receptor (EGFR) protein is highly expressed in soft tissue sarcoma (STS). We aimed to investigate the significance of phosphorylated-EGFR (pEGFR) and its activated-downstream signal transducers in STS tissue samples. A tissue microarray...

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Bibliographic Details
Main Authors: Jia-Lin Yang, Romi Das Gupta, David Goldstein, Philip J. Crowe
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:International Journal of Molecular Sciences
Subjects:
EGFR
pEGFR
pAkt
pERK
soft tissue sarcoma
grade
stage
overall survival
cancer specific survival
immunohistochemistry
Online Access:http://www.mdpi.com/1422-0067/18/6/1159

Internet

http://www.mdpi.com/1422-0067/18/6/1159

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