Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes.

Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes.

Phosphatidylinositides play important roles in cellular signaling and migration. Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) is an important phosphatidylinositide because it acts as a secondary messenger to trigger cell movement and proliferation. A high level of PI(3,4,5)P3 at the plasma...

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Bibliographic Details
Main Authors: Chun Liu, Sanghamitra Deb, Vinicius S Ferreira, Eric Xu, Tobias Baumgart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5813967?pdf=render

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http://europepmc.org/articles/PMC5813967?pdf=render

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