Proteomic analysis of energy metabolism and signal transduction in irradiated melanoma cells

Proteomic analysis of energy metabolism and signal transduction in irradiated melanoma cells

AIM: To analyze proteomic and signal transduction alterations in irradiated melanoma cells. METHODS: We combined stable isotope labeling with amino acids in cell culture (SILAC) with highly sensitive shotgun tandem mass spectrometry (MS) to create an efficient approach for protein quantification. Pr...

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Bibliographic Details
Main Authors:	Yang Shen, Yi-Lan Sun, Zhi-Tong Bing, Kai Shi, Lu-Bin Yan
Format:	Article
Language:	English
Published:	Press of International Journal of Ophthalmology (IJO PRESS) 2013-06-01
Series:	International Journal of Ophthalmology
Subjects:	melanoma cell 2D-LC-MS/MS stable isotope labeling with amino acids proteomic analysis X-ray irradiation protein-protein interaction
Online Access:	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693007/

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