The use of chicken and insect infection models to assess the virulence of African Salmonella Typhimurium ST313.

Over recent decades, Salmonella infection research has predominantly relied on murine infection models. However, in many cases the infection phenotypes of Salmonella pathovars in mice do not recapitulate human disease. For example, Salmonella Typhimurium ST313 is associated with enhanced invasive in...

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Bibliographic Details
Main Authors: Lizeth Lacharme-Lora, Siân V Owen, Richard Blundell, Rocío Canals, Nicolas Wenner, Blanca Perez-Sepulveda, Wai Yee Fong, Rachel Gilroy, Paul Wigley, Jay C D Hinton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007540