Vasohibin 2 decreases the cisplatin sensitivity of hepatocarcinoma cell line by downregulating p53.

Hepatocellular carcinoma (HCC) is a prevalent problem worldwide. Chemotherapy, especially cisplatin (CDDP)-based systemic chemotherapy, is the best option for advanced liver cancer. However, CDDP resistance is becoming common and hindering the clinical application of CDDP. Meanwhile, no consensus ha...

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Bibliographic Details
Main Authors: Zhanjun Li, Min Tu, Bei Han, Yuqing Gu, Xiaofeng Xue, Jie Sun, Qianqian Ge, Yi Miao, Zhuyin Qian, Wentao Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3942424?pdf=render