Chlamydia pan-genomic analysis reveals balance between host adaptation and selective pressure to genome reduction

Chlamydia pan-genomic analysis reveals balance between host adaptation and selective pressure to genome reduction

Abstract Background Chlamydia are ancient intracellular pathogens with reduced, though strikingly conserved genome. Despite their parasitic lifestyle and isolated intracellular environment, these bacteria managed to avoid accumulation of deleterious mutations leading to subsequent genome degradation...

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Bibliographic Details
Main Authors: Olga M. Sigalova, Andrei V. Chaplin, Olga O. Bochkareva, Pavel V. Shelyakin, Vsevolod A. Filaretov, Evgeny E. Akkuratov, Valentina Burskaia, Mikhail S. Gelfand
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Genomics
Subjects:
Chlamydia
Intracellular pathogens
Pan-genome
Genome evolution
Comparative genomics
PmpG
Online Access:http://link.springer.com/article/10.1186/s12864-019-6059-5

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http://link.springer.com/article/10.1186/s12864-019-6059-5

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