Computer simulations suggest a key role of membranous nanodomains in biliary lipid secretion.
The bile fluid contains various lipids that are secreted at the canalicular membrane of hepatocytes. As the secretion mechanism is still a matter of debate and a direct experimental observation of the secretion process is not possible so far, we used a mathematical model to simulate the extraction o...
Main Authors: | Johannes Eckstein, Nikolaus Berndt, Hermann-Georg Holzhütter |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-02-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4333117?pdf=render |
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