Computer simulations suggest a key role of membranous nanodomains in biliary lipid secretion.

The bile fluid contains various lipids that are secreted at the canalicular membrane of hepatocytes. As the secretion mechanism is still a matter of debate and a direct experimental observation of the secretion process is not possible so far, we used a mathematical model to simulate the extraction o...

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Bibliographic Details
Main Authors: Johannes Eckstein, Nikolaus Berndt, Hermann-Georg Holzhütter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4333117?pdf=render