Role of competition between polarity sites in establishing a unique front

Polarity establishment in many cells is thought to occur via positive feedback that reinforces even tiny asymmetries in polarity protein distribution. Cdc42 and related GTPases are activated and accumulate in a patch of the cortex that defines the front of the cell. Positive feedback enables spontan...

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Bibliographic Details
Main Authors: Chi-Fang Wu, Jian-Geng Chiou, Maria Minakova, Benjamin Woods, Denis Tsygankov, Trevin R Zyla, Natasha S Savage, Timothy C Elston, Daniel J Lew
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/11611