Combined EphB2 receptor knockdown with radiation decreases cell viability and invasion in medulloblastoma

Combined EphB2 receptor knockdown with radiation decreases cell viability and invasion in medulloblastoma

Abstract Background Medulloblastoma is one of the most common types of pediatric brain tumor characterized by the subpopulation of cells that exhibit high invasive potential and radioresistant properties. In addition, dysregulated function and signaling by Eph family of receptors have been shown to...

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Bibliographic Details
Main Authors: Shilpa Bhatia, Kellen Hirsch, Sanjana Bukkapatnam, Nimrah A. Baig, Ayman Oweida, Anastacia Griego, Dylan Calame, Jaspreet Sharma, Andrew Donson, Nicholas Foreman, Christopher Albanese, Sujatha Venkataraman, Rajeev Vibhakar, Sana D. Karam
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Cancer Cell International
Subjects:
EphB2
Radiosensitization
Medulloblastoma
Invasion
Online Access:http://link.springer.com/article/10.1186/s12935-017-0409-7

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http://link.springer.com/article/10.1186/s12935-017-0409-7

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