HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an <it>in vitro </it>study

<p>Abstract</p> <p>Background</p> <p>How HIV-1 enter into the eyes remains obscure. We postulated that HIV-1 Tat protein can alter the expression of specific tight-junction proteins and disturb the blood retinal barrier, and contributes to HIV trafficking into the eyes....

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Bibliographic Details
Main Authors: Lin Haotian, Yu Qiurong, Li Xiumei, Zhang Hui, Zhang Zhenping, Bai Ling, Yang Wenhui
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/8/77