The Epigenome as a therapeutic target for Parkinson's disease

The Epigenome as a therapeutic target for Parkinson's disease

Parkinson's disease (PD) is a common, progressive neurodegenerative disease characterised by degeneration of nigrostriatal dopaminergic neurons, aggregation of α-synuclein and motor symptoms. Current dopamine-replacement strategies provide symptomatic relief, however their effectiveness wear of...

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Bibliographic Details
Main Authors: Shane V Hegarty, Aideen M Sullivan, Gerard W O'Keeffe
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
Parkinson′s disease; epigenetics; methylation; acetylation; histone acetyltransferase; histone deacetylase; small molecules
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=11;spage=1735;epage=1738;aulast=Hegarty

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=11;spage=1735;epage=1738;aulast=Hegarty

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