Statins significantly repress rotavirus replication through downregulation of cholesterol synthesis

Rotavirus is the most common cause of severe diarrhea among infants and young children and is responsible for more than 200,000 pediatric deaths per year. There is currently no pharmacological treatment for rotavirus infection in clinical activity. Although cholesterol synthesis has been proven to p...

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Bibliographic Details
Main Authors: Shihao Ding, Bingting Yu, Anneke J. van Vuuren
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Gut Microbes
Subjects:
Online Access:http://dx.doi.org/10.1080/19490976.2021.1955643