Controlled localization of functionally active proteins to inclusion bodies using leucine zippers.

Inclusion bodies (IBs) are typically non-functional particles of aggregated proteins. However, some proteins in fusion with amyloid-like peptides, viral coat proteins, and cellulose binding domains (CBDs) generate IB particles retaining the original functions in cells. Here, we attempted to generate...

Full description

Bibliographic Details
Main Authors: Su-Lim Choi, Sang Jun Lee, Soo-Jin Yeom, Hyun Ju Kim, Young Ha Rhee, Heung-Chae Jung, Seung-Goo Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4045587?pdf=render