A Hypothetical-Mathematical Model of Acute Myeloid Leukaemia Pathogenesis

Acute myeloid leukaemia is defined by the expansion of a mutated haematopoietic stem cell clone, with the inhibition of surrounding normal clones. Haematopoiesis can be seen as an evolutionary tree, starting with one cell that undergoes several divisions during the expansion phase, afterwards losing...

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Bibliographic Details
Main Authors: Andrei Cucuianu, Radu Precup
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1080/17486700902973751