EXPERIMENTAL STUDY OF ANTI-THROMBOTIC ACTIVITY OF PENTOXYFILLIN MICROPARTICLES: BASED ON POLY-DL-LACTIDE-CO-GLYCOLIDE IN COMPARISON WITH PENTOXYFILLIN

The aim of the work was a comparative experimental study of the effect of oral administration of Pentoxifylline microparticles based on PLGA, and “standard” Pentoxifylline, on the ADP-induced platelet aggregation process in rats.Materials and methods. Pentoxifylline substance (100 mg/kg) was used as...

Full description

Bibliographic Details
Main Authors: T. V. Timchenko, V. E. Pogorelyi, A. V. Voronkov, L. M. Makarova, L. I. Scherbakova, V. A. Kompantsev, A. I. Medvetskyi, A. Y. Platonova
Format: Article
Language:Russian
Published: Pyatigorsk Medical and Pharmaceutical Institute - branch of Volgograd State Medical University 2019-05-01
Series:Farmaciâ i Farmakologiâ (Pâtigorsk)
Subjects:
Online Access:https://www.pharmpharm.ru/jour/article/view/365