In vitro antimicrobial activity of daptomycin alone and in adjunction with either amoxicillin, cefotaxime or rifampicin against the main pathogens responsible for bacterial meningitis in adults

In vitro antimicrobial activity of daptomycin alone and in adjunction with either amoxicillin, cefotaxime or rifampicin against the main pathogens responsible for bacterial meningitis in adults

ABSTRACT: Objectives: As daptomycin adjunction is currently under clinical evaluation in the multicentre phase II AddaMAP study to improve the prognosis of pneumococcal meningitis, the present work aimed at evaluating the in vitro antimicrobial activity of daptomycin-based combinations against some...

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Bibliographic Details
Main Authors: Thomas Maldiney, Dorian Bonnot, Nelson Anzala, Sandrine Albac, Delphine Labrousse, Emmanuelle Varon, Lucie Amoureux, Angélique Chapuis, Julien Bador, Catherine Neuwirth, Delphine Croisier, Pascal Chavanet
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Bacterial meningitis
Daptomycin
Antimicrobial association
Fractional inhibitory concentration
Time–kill kinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716521000734

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http://www.sciencedirect.com/science/article/pii/S2213716521000734

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