Elevated STAT3 Signaling-Mediated Upregulation of MMP-2/9 Confers Enhanced Invasion Ability in Multidrug-Resistant Breast Cancer Cells

The development of multidrug resistance greatly impedes effective cancer therapy. Recent advances in cancer research have demonstrated that acquisition of multidrug resistance by cancer cells is usually accompanied by enhanced cell invasiveness. Several lines of evidence indicated that cross activat...

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Bibliographic Details
Main Authors: Fei Zhang, Zhiyong Wang, Yanling Fan, Qiao Xu, Wei Ji, Ran Tian, Ruifang Niu
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/10/24772