Immunization of mice with recombinant protein CobB or AsnC confers protection against Brucella abortus infection.

Due to drawbacks of live attenuated vaccines, much more attention has been focused on screening of Brucella protective antigens as subunit vaccine candidates. Brucella is a facultative intracellular bacterium and cell mediated immunity plays essential roles for protection against Brucella infection....

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Bibliographic Details
Main Authors: Simei Fu, Jie Xu, Xianbo Li, Yongfei Xie, Yefeng Qiu, Xinying Du, Shuang Yu, Yaoxia Bai, Yanfen Chen, Tongkun Wang, Zhoujia Wang, Yaqing Yu, Guangneng Peng, Kehe Huang, Liuyu Huang, Yufei Wang, Zeliang Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3286461?pdf=render