Oregano Phytocomplex Induces Programmed Cell Death in Melanoma Lines via Mitochondria and DNA Damage

Oregano Phytocomplex Induces Programmed Cell Death in Melanoma Lines via Mitochondria and DNA Damage

Plant secondary metabolites possess chemopreventive and antineoplastic properties, but the lack of information about their exact mechanism of action in mammalian cells hinders the translation of these compounds in suitable therapies. In light of this, firstly, <i>Origanum vulgare</i> L....

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Bibliographic Details
Main Authors: Valentina Nanni, Gabriele Di Marco, Gianni Sacchetti, Antonella Canini, Angelo Gismondi
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Foods
Subjects:
oxidative stress
necroptosis
plant extract
secondary metabolite
γH2AX
copper
Online Access:https://www.mdpi.com/2304-8158/9/10/1486

Internet

https://www.mdpi.com/2304-8158/9/10/1486

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