Evaluation of the preclinical analgesic efficacy of naturally derived, orally administered oil forms of Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), and their 1:1 combination.

Evaluation of the preclinical analgesic efficacy of naturally derived, orally administered oil forms of Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), and their 1:1 combination.

Chronic neuropathic pain (NP) is a growing clinical problem for which effective treatments, aside from non-steroidal anti-inflammatory drugs and opioids, are lacking. Cannabinoids are emerging as potentially promising agents to manage neuroimmune effects associated with nociception. In particular, Δ...

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Bibliographic Details
Main Authors: Katja Linher-Melville, Yong Fang Zhu, Jesse Sidhu, Natalka Parzei, Ayesha Shahid, Gireesh Seesankar, Danny Ma, Zhi Wang, Natalie Zacal, Manu Sharma, Vikas Parihar, Ramesh Zacharias, Gurmit Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234176

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https://doi.org/10.1371/journal.pone.0234176

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