Prevalence of BRCA1 and BRCA2 pathogenic and likely pathogenic variants in non-selected ovarian carcinoma patients in Brazil

Prevalence of BRCA1 and BRCA2 pathogenic and likely pathogenic variants in non-selected ovarian carcinoma patients in Brazil

Abstract Background BRCA1/2 pathogenic (P) and likely pathogenic (LP) germline variants are frequent among patients with ovarian carcinoma. However, these variants have not been extensively characterized in patients with ovarian cancer in Brazil. Methods In this retrospective study we evaluated clin...

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Bibliographic Details
Main Authors: Deborah Porto Cotrim, Adriana Regina Gonçalves Ribeiro, Daniele Paixão, Diogo Cordeiro de Queiroz Soares, Rima Jbili, Natasha Carvalho Pandolfi, Camila Cezana, Carine de Cássia Mauro, Henrique Mantoan, Graziele Bovolim, Louise de Brot, Giovana Tardin Torrezan, Dirce Maria Carraro, Glauco Baiocchi, Maria Nirvana da Cruz Formiga, Alexandre A. B. A. da Costa
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Cancer
Subjects:
Ovarian cancer
BRCA1 and BRCA2 germline mutations
Brazil
Prevalence
Online Access:http://link.springer.com/article/10.1186/s12885-018-5235-3

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http://link.springer.com/article/10.1186/s12885-018-5235-3

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