Is FMR1 CGG Repeat Number Polymorphism Associated With Phenotypic Variation in the General Population? Report From a Cohort of 5,499 Adults

Is FMR1 CGG Repeat Number Polymorphism Associated With Phenotypic Variation in the General Population? Report From a Cohort of 5,499 Adults

FMR1 CGG repeat length was assayed in 5499 research participants (2637 men and 2862 women) in the Wisconsin Longitudinal Study (WLS), a population-based cohort. Most past research has focused on clinically-ascertained individuals with expansions in CGG repeats, either those with fragile X syndrome (...

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Bibliographic Details
Main Authors: Jinkuk Hong, Leann DaWalt, Mei Wang Baker, Elizabeth M. Berry-Kravis, Marsha R. Mailick
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Psychiatry
Subjects:
FMR1 CGG repeats
genotype-phenotype associations
genetic epidemiology
population cohorts
normal genetic variation
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.727085/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.727085/full

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