Nanodrug Delivery in Reversing Multidrug Resistance in Cancer Cells

Nanodrug Delivery in Reversing Multidrug Resistance in Cancer Cells

Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is known as multidrug resistance(MDR) which hinders chemotherapy efficacy. Potential factors for MDR includes enhanced drug detoxification, decreased drug uptake, increased intracellular nucleophiles levels, enhan...

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Bibliographic Details
Main Authors: Sonali eKapse-Mistry, Thirumala eGovender, Rohit eSrivastava, Mayur eYergeri
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Pharmacology
Subjects:
Tumor Microenvironment
multidrug resistance
drug efflux pumps
nanodrug delivery systems
theragnostic
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00159/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00159/full

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