MicroRNAs distinguish cytogenetic subgroups in pediatric AML and contribute to complex regulatory networks in AML-relevant pathways.

BACKGROUND: The role of microRNAs (miRNAs), important post-transcriptional regulators, in the pathogenesis of acute myeloid leukemia (AML) is just emerging and has been mainly studied in adults. First studies in children investigate single selected miRNAs, however, a comprehensive overview of miRNA...

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Bibliographic Details
Main Authors: Svenja Daschkey, Silja Röttgers, Anamika Giri, Jutta Bradtke, Andrea Teigler-Schlegel, Gunter Meister, Arndt Borkhardt, Pablo Landgraf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3572007?pdf=render