DNA display III. Solid-phase organic synthesis on unprotected DNA.

DNA-directed synthesis represents a powerful new tool for molecular discovery. Its ultimate utility, however, hinges upon the diversity of chemical reactions that can be executed in the presence of unprotected DNA. We present a solid-phase reaction format that makes possible the use of standard orga...

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Bibliographic Details
Main Authors: David R Halpin, Juanghae A Lee, S Jarrett Wrenn, Pehr B Harbury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC434150?pdf=render