Protein sites with more coevolutionary connections tend to evolve slower, while more variable protein families acquire higher coevolutionary connections [version 2; referees: 2 approved]
Background: Amino acid exchanges within proteins sometimes compensate for one another and could therefore be co-evolved. It is essential to investigate the intricate relationship between the extent of coevolution and the evolutionary variability exerted at individual protein sites, as well as the wh...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2017-07-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/6-453/v2 |