Structural characterization of ribosome recruitment and translocation by type IV IRES

Structural characterization of ribosome recruitment and translocation by type IV IRES

Viral mRNA sequences with a type IV IRES are able to initiate translation without any host initiation factors. Initial recruitment of the small ribosomal subunit as well as two translocation steps before the first peptidyl transfer are essential for the initiation of translation by these mRNAs. Usin...

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Bibliographic Details
Main Authors: Jason Murray, Christos G Savva, Byung-Sik Shin, Thomas E Dever, V Ramakrishnan, Israel S Fernández
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
IRES
cricket
paralysis
virus infection
ribosome
translocation
Online Access:https://elifesciences.org/articles/13567

Internet

https://elifesciences.org/articles/13567

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