Astaxanthin-loaded polymer-lipid hybrid nanoparticles (ATX-LPN): assessment of potential otoprotective effects

Abstract Background Ototoxicity is one of the major side effects of platinum-based chemotherapy, especially cisplatin therapy. To date, no FDA approved agents to alleviate or prevent this ototoxicity are available. However, ototoxicity is generally believed to be produced by excessive generation of...

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Bibliographic Details
Main Authors: Jiayi Gu, Yuming Chen, Ling Tong, Xueling Wang, Dehong Yu, Hao Wu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12951-020-00600-x