A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism

A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism

mRNA translation efficiency is regulated in response to stimuli. Here the authors employ mass spectrometry analysis of ribosome fractions and show that under hypoxia, oxygen-sensitive RNA binding proteins enhance the translation efficiency of glycolysis pathway transcripts.

Bibliographic Details
Main Authors: J. J. David Ho, Nathan C. Balukoff, Phaedra R. Theodoridis, Miling Wang, Jonathan R. Krieger, Jonathan H. Schatz, Stephen Lee
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16504-1

Internet

https://doi.org/10.1038/s41467-020-16504-1

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