Understanding the cross-resistance of oseltamivir to H1N1 and H5N1 influenza A neuraminidase mutations using multidimensional computational analyses

Ashona Singh, Mahmoud E Soliman School of Health Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa Abstract: This study embarks on a comprehensive description of the conformational contributions to resistance of neuraminidase (N1) in H1N1 and H5N1 to oseltamivir, using compara...

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Bibliographic Details
Main Authors: Singh A, Soliman ME
Format: Article
Language:English
Published: Dove Medical Press 2015-07-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/understanding-the-cross-resistance-of-oseltamivir-to-h1n1-and-h5n1-inf-peer-reviewed-article-DDDT