Direct Sensing of Nutrients via a LAT1-like Transporter in Drosophila Insulin-Producing Cells

Direct Sensing of Nutrients via a LAT1-like Transporter in Drosophila Insulin-Producing Cells

Dietary leucine has been suspected to play an important role in insulin release, a hormone that controls satiety and metabolism. The mechanism by which insulin-producing cells (IPCs) sense leucine and regulate insulin secretion is still poorly understood. In Drosophila, insulin-like peptides (DILP2...

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Bibliographic Details
Main Authors: Gérard Manière, Anna B. Ziegler, Flore Geillon, David E. Featherstone, Yael Grosjean
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Subjects:
amino acid transporter
minidiscs
food
starvation
Drosophila insulin-like peptides
insulin-producing cells
glutamate dehydrogenase
glycemia
growth
Drosophila
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716312025

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http://www.sciencedirect.com/science/article/pii/S2211124716312025

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