Expression of VP7, a Bluetongue virus group specific antigen by viral vectors: analysis of the induced immune responses and evaluation of protective potential in sheep.

Bluetongue virus (BTV) is an economically important Orbivirus transmitted by biting midges to domestic and wild ruminants. The need for new vaccines has been highlighted by the occurrence of repeated outbreaks caused by different BTV serotypes since 1998. The major group-reactive antigen of BTV, VP7...

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Main Authors: Coraline Bouet-Cararo, Vanessa Contreras, Agathe Caruso, Sokunthea Top, Marion Szelechowski, Corinne Bergeron, Cyril Viarouge, Alexandra Desprat, Anthony Relmy, Jean-Michel Guibert, Eric Dubois, Richard Thiery, Emmanuel Bréard, Stephane Bertagnoli, Jennifer Richardson, Gilles Foucras, Gilles Meyer, Isabelle Schwartz-Cornil, Stephan Zientara, Bernard Klonjkowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0111605