Stem Cell-Derived, microRNA-Carrying Extracellular Vesicles: A Novel Approach to Interfering with Mesangial Cell Collagen Production in a Hyperglycaemic Setting.

Extracellular vesicles (EVs) that are derived from stem cells are proving to be promising therapeutic options. We herein investigate the therapeutic potential of EVs that have been derived from different stem cell sources, bone-marrow (MSC) and human liver (HLSC), on mesangial cells (MCs) exposed to...

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Bibliographic Details
Main Authors: Sara Gallo, Maddalena Gili, Giusy Lombardo, Alberto Rossetti, Arturo Rosso, Patrizia Dentelli, Gabriele Togliatto, Maria Chiara Deregibus, Daniela Taverna, Giovanni Camussi, Maria Felice Brizzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5017750?pdf=render