Lack of Androgen Receptor Expression Selects for Basal-Like Phenotype and Is a Predictor of Poor Clinical Outcome in Non-Metastatic Triple Negative Breast Cancer

Lack of Androgen Receptor Expression Selects for Basal-Like Phenotype and Is a Predictor of Poor Clinical Outcome in Non-Metastatic Triple Negative Breast Cancer

Background: Androgen receptor (AR) has emerged as a significant favorable prognostic indicator in estrogen receptor expressing (ER+) breast cancer (BCa); however, its clinical and biological relevance in triple negative breast cancer (TNBC) and association with cancer stem cell (CSC) markers remain...

Full description

Bibliographic Details
Main Authors: Nazia Riaz, Romana Idress, Sadia Habib, El-Nasir Lalani
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
androgen receptor
triple negative breast cancer
basal-like breast cancer
prognosis
cancer stem cells
biomarkers
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01083/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01083/full

Similar Items