Fasciola hepatica Surface Coat Glycoproteins Contain Mannosylated and Phosphorylated N-glycans and Exhibit Immune Modulatory Properties Independent of the Mannose Receptor.

Fasciola hepatica Surface Coat Glycoproteins Contain Mannosylated and Phosphorylated N-glycans and Exhibit Immune Modulatory Properties Independent of the Mannose Receptor.

Fascioliasis, caused by the liver fluke Fasciola hepatica, is a neglected tropical disease infecting over 1 million individuals annually with 17 million people at risk of infection. Like other helminths, F. hepatica employs mechanisms of immune suppression in order to evade its host immune system. I...

Full description

Bibliographic Details
Main Authors: Alessandra Ravidà, Allison M Aldridge, Nicole N Driessen, Ferry A H Heus, Cornelis H Hokke, Sandra M O'Neill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4841591?pdf=render

Internet

http://europepmc.org/articles/PMC4841591?pdf=render

Similar Items