Sp1 is involved in H<sub>2</sub>O<sub>2</sub>-induced PUMA gene expression and apoptosis in colorectal cancer cells

<p>Abstract</p> <p>Background</p> <p>Reactive oxygen species (ROS) are intricately involved in tumor progression through effects on proliferation, apoptosis and metastasis. But how ROS works is not well understood. In previous study, we found PUMA (p53-upregulated modul...

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Bibliographic Details
Main Authors: Wang Jide, Geng Yan, Lin Shiyong, Wang Jing, Wang Xinying, Jiang Bo
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/27/1/44