Ginsenoside Rb3 regulates energy metabolism and apoptosis in cardiomyocytes via activating PPARα pathway

Ginsenoside Rb3 regulates energy metabolism and apoptosis in cardiomyocytes via activating PPARα pathway

Heart failure (HF) leads to an increase in morbidity and mortality globally. Disorders of energy metabolism and apoptosis of cardiomyocytes are critically involved in the progression of HF. Ginsenoside Rb3 (G-Rb3) is a natural product derived from ginseng that has cardio-protective effect. The pharm...

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Bibliographic Details
Main Authors: Xu Chen, Qiyan Wang, Mingyan Shao, Lin Ma, Dongqing Guo, Yan Wu, Pengrong Gao, Xiaoping Wang, Weili Li, Chun Li, Yong Wang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ginsenoside Rb3
Heart failure
PPARα
Fatty acid
Oxidation
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219334262

Internet

http://www.sciencedirect.com/science/article/pii/S0753332219334262

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