γ-Aminobutyric AcidB(GABAB)-Receptor Mediation of Different In Vivo Effects of γ-Butyrolactone

The endogenous brain constituent, γ-hydroxybutyric acid (GHB), as well as its prodrug, γ-butyrolactone (GBL), have recently gained interest in the drug addiction field due to their abuse potential and fatalities caused by overdose. It is known that GHB has two sites of actions: the γ-aminobutyric ac...

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Bibliographic Details
Main Authors: Mauro A.M. Carai, Carla Lobina, Paola Maccioni, Claudia Cabras, Giancarlo Colombo, Gian Luigi Gessa
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319315130