Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects.

BACKGROUND: Addiction and major depression are mental health problems associated with stressful events in life with high relapse and reoccurrence even after treatment. Many laboratories were not able to detect the presence of cannabinoid CB2 receptors (CB2-Rs) in healthy brains, but there has been d...

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Bibliographic Details
Main Authors: Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Paul A Meozzi, Lester Myers, Alex Perchuk, Zoila Mora, Patricia A Tagliaferro, Eileen Gardner, Alicia Brusco, B Emmanuel Akinshola, Bruce Hope, Javier Lujilde, Toshiya Inada, Shinya Iwasaki, David Macharia, Lindsey Teasenfitz, Tadao Arinami, George R Uhl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2241668?pdf=render