Fast and effective mitochondrial delivery of ω-Rhodamine-B-polysulfobetaine-PEG copolymers

Fast and effective mitochondrial delivery of ω-Rhodamine-B-polysulfobetaine-PEG copolymers

Abstract Mitochondrial targeting and entry, two crucial steps in fighting severe diseases resulting from mitochondria dysfunction, pose important challenges in current nanomedicine. Cell-penetrating peptides or targeting groups, such as Rhodamine-B (Rho), are known to localize in mitochondria, but l...

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Bibliographic Details
Main Authors: Nobuyuki Morimoto, Riho Takei, Masaru Wakamura, Yoshifumi Oishi, Masafumi Nakayama, Makoto Suzuki, Masaya Yamamoto, Françoise M. Winnik
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-19598-2

Internet

https://doi.org/10.1038/s41598-018-19598-2

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