Organocatalyzed Intramolecular Carbonyl-Ene Reactions

An organocatalyzed intramolecular carbonyl-ene reaction was developed to produce carbocyclic and heterocyclic 5- and 6-membered rings from a citronellal-derived trifluoroketone and a variety of aldehydes. A phosphoramide derivative was found to promote the cyclization of the trifluoroketone, whereas...

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Bibliographic Details
Main Authors: Heidi A. Dahlmann, Amanda J. McKinney, Maria P. Santos, Lindsey O. Davis
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/6/713