Synovial tissue macrophages: friend or foe?
Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce pathogenic tumour necrosis factor. During sustai...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2017-12-01
|
Series: | RMD Open |
Online Access: | https://rmdopen.bmj.com/content/3/2/e000527.full |