Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism

Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism

The post-translational modification of proteins has been shown to be extremely important in prokaryotes. Using a highly sensitive mass spectrometry-based proteomics approach, we have characterized the acetylome of B. burgdorferi. As previously reported for other bacteria, a relatively low number (5%...

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Bibliographic Details
Main Authors: Sébastien Bontemps-Gallo, Charlotte Gaviard, Crystal L. Richards, Takfarinas Kentache, Sandra J. Raffel, Kevin A. Lawrence, Joseph C. Schindler, Joseph Lovelace, Daniel P. Dulebohn, Robert G. Cluss, Julie Hardouin, Frank C. Gherardini
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Microbiology
Subjects:
Lyme disease
Borrelia
acetylation
metabolism
regulation-post-translational
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02036/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02036/full

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